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Updated: Mar 29, 2026

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比特里斯:贝叶斯精细映射从总结数据使用深度变异推理

Sayan Ghosal1, Michael C Schatz2, Archana Venkataraman3

  • 1Chan Zuckerberg Initiative Foundation, Redwood City, CA 94065, United States.

Bioinformatics (Oxford, England)
|October 3, 2024
PubMed
概括

BEATRICE是一种使用层次贝叶斯模型的新框架,可以从GWAS数据中准确识别因果变异. 它的性能优于现有方法,特别是在阿尔茨海默氏症遗传学中发现APOE ε2等位基因.

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