热浪和上尿路结石的发病率:根据热浪定义,疾病亚型和脆弱人群的效果修改
Chenlu Yang1, Shi Li1, Yunmeng Yang1
1Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, 450001, China.
Urolithiasis
|October 3, 2024
概括
升高的热浪增加了尿病风险,特别是尿路结石. 最佳的热浪定义是两天的温度高于第93百分位,与石头疾病的7.40%可归因部分相关.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 尿酸结石 (结石) 是一种热性疾病,由于气候变化,其发病率越来越高.
- 热浪对不同尿病亚型的确切影响以及热浪对这种疾病的最佳定义仍然不清楚.
研究的目的:
- 为了研究热浪与上尿路结石 (尿路结石) 发病率之间的关联.
- 确定热浪的最佳定义,以预测尿病风险.
- 探索性别,年龄和疾病亚型对这种关联的影响.
主要方法:
- 利用分布式滞后线性模型分析了32个定义的热浪情景和上尿路结石发病率之间的关联.
- 采用元分析来对热浪强度 (低,中,高) 的相对风险 (RR) 和归因分数 (AF) 进行聚合.
- 使用AF,RR和准Akaike信息标准 (QAIC) 的综合得分选择了最佳的热浪定义.
主要成果:
- 在热浪和上泌尿道结石之间发现了显著的关联,主要是尿道结石.
- 在低强度的热浪中观察到最高可归因分数 (AF).
- 最佳的热浪定义被确定为至少连续两天平均温度超过第93百分位,AF为7.40% (95%CI:2.02%,11.27%).
- 热浪相关的尿病风险在男性和中年成年人中显著,但在女性或其他年龄组中没有.
结论:
- 热浪,特别是连续几天的高温,显著增加尿道结石的风险.
- 公共卫生战略应纳入特定区域的热浪定义,以减轻尿病负担.
- 在热浪期间对男性和中年人群进行有针对性的干预可能是必要的,以减少石头疾病的发生率.
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