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Updated: Jul 17, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
22:27

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

在DNA上合成硫丹架,用于对焦DNA编码图书馆的构建

Xianfu Fang1,2, Yunzhu Ju1, Jiayou Wang1

  • 1Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.

Organic letters
|October 3, 2024
PubMed
概括

我们开发了一种与DNA兼容的方法,以创建聚焦于 thiohydantoin 的 DNA 编码库. 这种强大的合成是多功能性的,使得人们能够访问有价值的化学图书馆,用于药物发现.

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Published on: August 12, 2019

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DNA as a Genetic Template02:05

DNA as a Genetic Template

Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...