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在移植先眼睛中植入初级角质假体的视觉结果

Camryn Thompson¹, Cason Robbins¹, Rami Gabriel¹

¹Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States of America.

|October 3, 2024

概括

初级角膜假体 (Kpro) 在角膜移植失败后,提供与二级Kpro相似的视觉结果. 初级Kpro患者显示出更好的最终视力敏度的趋势,并没有增加并发症.

科学领域:

眼科医生眼科眼科
角膜外科手术角膜外科手术
假肢植入物是一种植入物.

背景情况:

角膜整形 (Kpro) 植入是穿透角膜整形后预后不佳的眼睛的一个选择.
淋巴干细胞缺陷 (LSCD) 是Kpro在之前进行角膜移植的眼睛中的常见指示.

研究的目的:

为了比较初级Kpro植入 (第一次角膜手术) 和二次Kpro植入 (之前的角膜移植后) 之间的视觉结果.
为了评估初级与二级Kpro.患者的并发症和视力敏度.

主要方法:

从2005年至2020年期间,对77名患者进行了84次Kpro植入的回顾性审查.
在没有先前角膜移植的情况下接受初级Kpro的12只眼睛的识别.
主要和次要Kpro组之间的视力敏度和并发症率的比较.

主要成果:

初级Kpro适用于LSCD (41.7%),角膜痕 (25.0%) 和神经营养角膜 (16.7%).
在初级和二级Kpro组之间,手术前,3个月和最终随访 (平均3.06年) 的平均视力敏度相似.
没有观察到随访时间或青光眼,内眼炎,后置膜或视网膜脱落的发生率的显著差异. 眼睛逐渐没有光感知,所有人都经历了二级Kpro.

结论:

初级和二级Kpro植入产生可比的视力敏度结果.
与二级Kpro相比,接受初级Kpro的眼睛显示出更好的最终术后视力敏度的趋势.
两组之间没有发现主要并发症的显著差异.

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