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Updated: May 7, 2026

Purification of Hsp104, a Protein Disaggregase
07:17

Purification of Hsp104, a Protein Disaggregase

Published on: September 30, 2011

Hsp104的中间域可以确保基板在加工后具有功能

Hannah E Buchholz1, Jane E Dorweiler1, Sam Guereca1

  • 1Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin, United States of America.

PLoS genetics
|October 3, 2024
PubMed
概括

像Hsp104这样的分子伴侣分解蛋白质. Hsp104中位域的工程变体可以分解聚合物,但会损害蛋白质功能,揭示其在维持蛋白质活性方面的关键作用.

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