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带有中尖的自我限制性的流行病学 (SeLECTS):使用初级保健记录进行的一项人口研究
Arron S Lacey1, Carys B Jones1, Seung Gwan Ryoo1
1Swansea University Medical School, Swansea University, Swansea, UK.
Seizure
|October 3, 2024
概括
这项研究发现,自限性的发病率与先前报告的中尖峰 (SeLECTS) 相比较低,并且随着时间的推移没有变化. 建议对有SELECTS的儿童进行神经发育问题的查.
科学领域:
- 儿科神经学 儿科神经学
- 发病学 (Epileptology) 是一个专业的学科.
- 公共卫生 公共卫生
背景情况:
- 有限的流行病学数据存在于自限性与中尖峰 (SeLECTS).
- 了解SELECTS发病率,社会经济关联和并发症对于有效的公共卫生战略至关重要.
- 之前的研究还没有完全阐明SELECTS在儿童群体中的流行病学.
研究的目的:
- 为了确定SELECTS在儿童中的发病率.
- 调查Selects发病率与社会经济贫困之间的关联.
- 为了评估神经发育并发症的患病率在儿童与SELECTS.
主要方法:
- 使用威尔士 (2004-2017年) 相关的初级保健和人口统计数据进行的回顾性队列研究.
- 在0-16岁儿童中使用初级保健诊断代码识别SELECTS病例.
- 混合效应 普森回归分析,以评估时间趋势和社会经济关联.
主要成果:
- 在6732名患有的儿童中,共有186名 (3%) 被诊断出患有SeLECTS.
- 2017年SELECTS的原始发病率为1.1 / 100,000/年,低于之前报告的.
- 18%的SELECTS儿童患有神经发育障碍或学校问题,一半接受抗发作药物治疗.
结论:
- 选择的发生率可能低于先前估计的,可能是由于记录不足.
- 虽然存在样本规模限制,但在SELECTS发生率和社会经济贫困之间没有发现显著的关联.
- 对于被诊断患有SELECTS的儿童,建议对神经发育和学习并发症进行例行查.
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