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微质介导的神经元死亡需要TNF,并被突变的亨廷丁激增

Alexander P Young1, Eileen M Denovan-Wright1

  • 1Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.

Pharmacological research
|October 3, 2024
PubMed
概括

微质细胞有助于亨廷顿病 (HD) 中的神经元死亡. 疾病神经元对微质炎症因子过敏,瘤死因子 (TNF) 对细胞死亡至关重要.

关键词:
细胞因子 (cytokines) 是一种细胞因子.亨廷顿病是亨廷顿氏病的一种疾病.干扰素是干扰素的一种.这就是JAK-STAT.微质细胞中的微质细胞神经炎症是一种神经炎症.这就是TNF TNF.

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