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Updated: Jun 11, 2025

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
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在肺腺癌中,Paeoniae radix通过极光 B 路径抑制克服了对EGFR-TKI的耐药性

Heerim Yeo1, Haeseung Lee2, Sang-Min Park1

  • 1College of Pharmacy, Chungnam National University, Republic of Korea.

Life sciences
|October 3, 2024
PubMed
概括

结合EGFR-TKIs的Paeoniae Radix (PR) 可能可以克服肺腺癌的耐药性. 这种天然产品抑制了Aurora B通路,增强了EGFR突变LUAD的亡和药物反应.

关键词:
组合疗法是一种联合疗法.药物耐药性 药物耐药性 药物耐药性草药是一种草药.肺部腺癌瘤是肺部腺癌.自然产品是一种自然产品.转录组 转录组就是一个转录组.

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