麦克马斯特咳严重性问卷 (MCSQ):用于耐火性慢性咳患者的咳严重性仪器
Elena Kum1,2, Gordon H Guyatt1,2, Rayid Abdulqawi3
1Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
The European respiratory journal
|October 3, 2024
概括
一个新的8项麦克马斯特咳严重性问卷 (MCSQ) 有效地测量了耐火性慢性咳 (RCC) 的严重性. 这一经验证的患者报告结果为评估RCC患者治疗影响提供了可靠的数据.
科学领域:
- 临床评估和患者报告的结果.
- 呼吸系统医学和肺病学
- 治疗疗效和结果测量.
背景情况:
- 咳的严重程度是评估耐药慢性咳 (RCC) 治疗方法的关键终点.
- 现有的措施可能无法完全捕捉患者对咳严重程度的体验.
- 对于RCC,需要一个经过验证的患者报告的结果测量.
研究的目的:
- 开发和验证一种新的患者报告的结局测量方法,用于RCC.咳严重程度.
- 为了创建麦克马斯特咳严重性问卷 (MCSQ).
主要方法:
- 通过调查,焦点小组和专家咨询 (51项) 来生成项目.
- 通过患者对频率和重要性的输入来减少项目,然后进行探索性因子和拉什分析.
- 使用内部一致性,人分离指数和与视觉模拟尺度的融合有效性进行验证.
主要成果:
- 开发了最终的8项MCSQ,包括两个领域:强度和频率.
- 该MCSQ显示出高的内部一致性 (克朗巴赫的α=0.89) 和可靠性 (人与人分离指数0.89).
- 通过视觉模拟尺度 (r=0.76) 观察到强的收有效性.
结论:
- 8项MCSQ是测量RCC患者咳严重程度的有效和可靠的仪器.
- 最初的证据支持MCSQ在临床实践中的实用性.
- 建议进行进一步的研究,以评估其测量随时间变化的能力.
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