在COVID-19大流行期间,有抑郁病史的人的睡眠模式变化:一个自然实验
Mirim Shin1, Jacob J Crouse2, Enda M Byrne3
1The University of Sydney Brain and Mind Centre, Camperdown, New South Wales, Australia mirim.shin@sydney.edu.au.
BMJ mental health
|October 3, 2024
概括
由于COVID-19大流行,抑郁病史患者的睡眠模式发生了变化,许多人从最佳睡眠时间转移. 预先存在的心理健康,遗传因素和痛苦影响了这些睡眠变化.
科学领域:
- 精神病学是一个精神病学.
- 睡眠医学 睡眠医学
- 遗传学 遗传学是一种遗传学.
背景情况:
- 随着COVID-19大流行,引入了重要的压力因素,但也增加了睡眠和清醒时间表的灵活性.
- 了解与流行病相关的睡眠变化至关重要,尤其对弱势群体,如有抑郁病史的人,至关重要.
研究的目的:
- 为了检查流行病对有抑郁病史的个体睡眠模式的影响.
- 确定预测这些睡眠模式变化的社会人口统计学,临床和遗传因素.
主要方法:
- 利用了澳大利亚抑郁症遗传学研究中的6453名成年人的数据,比较了大流行前 (2016-2018) 和大流行 (2020-2021) 调查答案.
- 参与者被分为"短睡眠" (<6小时),"最佳睡眠" (6-8小时) 和"长睡眠" (>8小时),重点关注患有大流行前最佳睡眠的人.
- 分析了睡眠时间的变化以及相关的人口,临床和遗传因素,包括抑郁症遗传分数和失眠严重程度.
主要成果:
- 在大流行前,70%的人报告了最佳睡眠,在大流行期间下降到49%.
- 在那些在疫情前有最佳睡眠的人中,57%的人保持了最佳睡眠,而16%的人转向短睡眠和27%的人转向长睡眠.
- 转变为睡眠短暂与疫情前更糟糕的心理健康,更高的失眠和更高的抑郁遗传分数有关. 长时间睡眠的转变与年轻的年龄,更高的焦虑,晚上的时代型和高的抑郁遗传分数有关.
结论:
- COVID-19 流行病作为一种自然实验,在有抑郁病史的人群中引起了显著的睡眠模式转变.
- 流行前的特征,包括心理健康,痛苦,失眠和遗传倾向,预测了这些睡眠变化.
- 对这些睡眠动态的洞察力可以为面临重大生活挑战的抑郁症患者提供量身定制的干预指导.
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