在老老鼠中,次最大特异性抵抗训练增加了序列瘤数量,并改善了动态肌肉性能
Avery Hinks1, Ethan Vlemmix1, Geoffrey A Power1
1Department of Human Health and Nutritional Sciences, College of Biological Sciences, University of Guelph, Guelph, Ontario, Canada.
Physiological reports
|October 3, 2024
概括
亚最大偏心训练通过增加序列瘤数 (SSN) 来改善老老鼠的肌肉功能. 这种有益的适应增强了肌肉性能,并减少了老肌肉中的被动紧张.
科学领域:
- 运动生理学 运动生理学
- 骨肌肉生物学 骨肌肉生物学
- 衰老研究研究 衰老研究
背景情况:
- 与年龄相关的肌肉损失 (sarcopenia) 与瘤损失和机械功能降低有关.
- 在此之前,最大偏心训练未能增加连续瘤数 (SSN) 和衰老肌肉的性能恶化.
- 一个亚最大的奇特训练刺激可能更有效地适应老肌肉.
研究的目的:
- 为了确定亚最大偏心训练是否可以增加老老鼠的SSN.
- 评估亚最大偏心训练对老老鼠肌肉机械功能的影响.
主要方法:
- 十二只32个月大的雄性大鼠接受了为期4周的亚最大 (60%的最大) 奇特的足部曲训练.
- 在体外的评估包括等比扭矩,被动扭矩-角度关系,和等离子扭矩-速度-功率.
- 使用激光衍射,分析了SSN的唯一和中间胃角肌肉.
主要成果:
- 索莱斯肌肉中SSN增加了11%,中部胃腰肌肉中增加了8%.
- 最佳扭矩产生转移到更长的肌肉长度.
- 被动扭矩下降了42%,而峰值同位素功率增加了23%.
结论:
- 亚最大偏心训练促进老化肌肉的有益适应.
- 这种训练策略增加了SSN,降低了被动肌肉张力,并提高了老老鼠的动态收缩性能.
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