饮食中的抗氧化剂指数与2型糖尿病患者的功能指标的关联:一个横截面研究
Noushin Omid1,2, Ensieh Nasli Esfahani1, Razieh Tabaeifard2
1Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Scientific reports
|October 3, 2024
概括
通过饮食抗氧化剂指数 (DAI) 测量较高的饮食抗氧化剂摄入量,与2型糖尿病成年人的更好的功能有关. 这表明抗氧化剂可能会在这个人群中支持脏健康.
科学领域:
- 营养科学 营养科学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
背景情况:
- 2型糖尿病是慢性病的主要危险因素.
- 氧化压力在糖尿病病中起着重要作用.
- 饮食中的抗氧化剂可能会对脏损伤产生保护作用.
研究的目的:
- 调查饮食中抗氧化剂指数与2型糖尿病成年人功能之间的关联.
- 为了确定特定的饮食抗氧化剂措施是否与脏健康标志物相关.
主要方法:
- 对240名患有2型糖尿病的成年人进行横截面研究.
- 饮食摄入量通过三个24小时回忆评估.
- 计算了饮食总抗氧化剂容量 (DTAC),饮食抗氧化剂指数 (DAI) 和饮食抗氧化剂质量评分 (DAQS).
- 从医疗记录中提取的功能指标 (血清肌素,尿素,BUN,GFR).
主要成果:
- 与最低的三位数相比,最高的DAI三位数与较低的血清肌素,减少的尿素和更高的淋巴细胞过率 (GFR) 相关.
- 在DAQS和GFR之间发现了显著的正相关性 (β:0.20;P=0.005).
- 在DAI和GFR (β:0.14;P=0.06) 之间观察到微显的直接关系.
- 在DTAC和GFR之间没有发现显著的关联 (β-0.02;P=0.80).
结论:
- 饮食中较高的抗氧化剂摄入量,特别是通过DAI和DAQS进行评估,可能与2型糖尿病患者的功能改善有关.
- 虽然结果表明潜在的益处,但需要进一步的研究来强烈证实饮食中抗氧化剂在保护功能中的作用.
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