在重症监护室发生的急性损伤:巴西亚马逊地区基于人口的前性队列研究
Fernando A F Melo1, Emmanuel A Burdmann2, Etienne Macedo3
1Division of Urology, Acre Federal University, Rio Branco, Acre, Brazil.
Scientific reports
|October 3, 2024
概括
巴西亚马逊地区的重症患者经历了急性损伤 (AKI) 的高发病率. 风险因素和结果反映了高收入国家,但在这个服务不足的地区,AKI死亡率明显更高.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临界护理医学 临界护理医学
- 流行病学 流行病学
背景情况:
- 巴西亚马逊地区面临医疗保健差异,影响了重症患者的护理.
- 急性损伤 (AKI) 是重症监护室 (ICU) 的一个重大问题.
研究的目的:
- 确定巴西亚马逊地区重症患者中AKI的发病率,风险因素和结果.
- 将该地区的AKI流行病学与高收入国家的发现进行比较.
主要方法:
- 一项前性队列研究,涉及1029名成年患者在巴西阿克里州里奥布兰科的三个重症监护室.
- 数据收集时间为2014年2月至2016年2月,评估AKI发病率,风险因素 (例如年龄,APACHE II分数,液体平衡) 和死亡率.
主要成果:
- AKI的发生率为53.3%.
- 关键的危险因素包括年龄较高,非手术状态,病房入院,APACHE II分数升高和体液平衡阳性.
- AKI与ICU死亡率增加有关 (aOR2.03),独立预测因素包括年龄,非手术状态,败血症,休克,血管活性药物使用,机械通风和流体过载.
结论:
- 在巴西亚马逊地区的重症患者中,AKI的发病率特别高.
- 虽然AKI病因和风险因素与全球数据一致,但死亡率要高得多,这凸显了改善医疗保健资源和干预措施的迫切需要.
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