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Ming Liu¹, Yunpeng Gou¹, Bing Zou¹

¹Department of Pediatric Surgery, Suining Central Hospital, Suining, Sichuan Province, China.

Scientific reports

|October 3, 2024

概括

吸烟与男性的丸激素水平有关. 较高的血清胆氨酸 (吸烟标志物) 最初与的增加相关,但水平在特定值以上显著下降.

科学领域:

内分泌学在内分泌学.
毒理学毒理学毒理学
公共卫生公共卫生

背景情况:

吸烟和男性丸激素水平之间的关联受到争论.
血清胆固醇是吸烟强度和烟草烟雾暴露的经过验证的生物标志物.

研究的目的:

在成年男性中研究血清丁水平和总丸激素度之间的关系.
识别潜在的非线性关联和值效应.

主要方法:

利用美国国家健康和营养检查调查 (NHANES) 的数据.
采用加权线性回归,子组分析和平滑曲线拟合.
分析值效应以确定转折点.

主要成果:

总共有7797名成年男性被纳入分析.
在血清胆固醇和总丸激素之间观察到一种积极的关联 (β:0.05,95%CI:0.02,0.09).
在487 ng/ml血清胆固醇的点被确定,超出该点后,水平下降.

结论:

在成年男性中,血清丁胺的升高与总丸激素有积极的关联.
在非常高的血清丁度下,这种关系可能会逆转,表明复杂的相互作用.

关键词:

国家健康和营养检查调查 (NHANES)在血清中含有胆固醇. 血清中含有胆固醇.吸烟吸烟吸烟吸烟总体丸激素总体丸激素

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