相关概念视频
Ligand Binding and Linkage
3.0K
3.0K
Genome Annotation and Assembly
18.8K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
18.8K
Ligand Binding Sites
7.6K
7.6K
Conserved Binding Sites
1.7K
1.7K
Hybridization of Atomic Orbitals I
46.6K
The mathematical expression known as the wave function, ψ, contains information about each orbital and the wavelike properties of electrons in an isolated atom. When atoms are bound together in a molecule, the wave functions combine to produce new mathematical descriptions that have different shapes. This process of combining the wave functions for atomic orbitals is called hybridization and is mathematically accomplished by the linear combination of atomic orbitals. The new orbitals that...
46.6K
Molecular Models
38.0K
Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
38.0K
您也可能阅读
相关文章
通过共同作者、期刊和引用图与本文相关的文章。
排序
Same author
A Framework for a Standard-Enabled FAIR Data Management Workflow for Synthetic Biology.
ACS synthetic biology·2026
Same author
A Decade of SBOL Visual: Growing Adoption of a Diagram Standard for Engineering Biology.
ACS synthetic biology·2025
Same author
Genetic Network Design Automation with LOICA.
Methods in molecular biology (Clifton, N.J.)·2024
标准化金门大会元数据表示使用SBOL.
Gonzalo Vidal1,2, Carolus Vitalis3, Johan Guillén4
1Interdisciplinary Computing and Complex Biosystems, School of Computing, Newcastle University, Newcastle upon Tyne, UK. gonzalo.vidalpena@colorado.edu.
Methods in molecular biology (Clifton, N.J.)
|October 3, 2024
概括
合成生物学使用工程原理来设计生物系统,通常是通过修改DNA. 一个新的软件工具有助于创建DNA构建计划,用于组装反应和存储元数据.
科学领域:
- 合成生物学和工程生物学 合成生物学和工程生物学
- 在DNA合成和组装过程中.
- 生物信息学和计算生物学
背景情况:
- 合成生物学将工程原理应用于生物系统,经常涉及DNA修饰.
- 合成和组装DNA部分对于工程生物系统至关重要.
- 现有的组装标准 (MoClo,Phytobricks,Loop) 是基于金门组装的.
研究的目的:
- 介绍一个软件工具,用于创建合成生物学开放语言 (SBOL) 的DNA构建计划的表示.
- 为了能够模拟类型IIS介导的组合反应.
- 为了促进对DNA组装工作流程的相关元数据的存储.
主要方法:
- 开发一个用于生成SBOL表示的软件工具.
- 实施IIS类介导组合反应的模拟.
- 集成元数据存储能力.
主要成果:
- 一个功能性的软件工具,用于创建SBOL构建计划.
- 模拟DNA组装反应的能力.
- 集成元数据的有效存储和检索.
结论:
- 开发的软件工具简化了设计和模拟DNA组装的过程.
- 它增强了合成生物学研究中的沟通和可重现性.
- 便于在生物工程中整合设计和自动化.


