多发性硬化症的抑郁症状:与身体组成,身体活动和功能能力的联系
Elżbieta Cieśla1, Elżbieta Jasińska1, Martyna Głuszek-Osuch1
1Institute of Health Sciences, Jan Kochanowski University, Collegium Medicum, Kielce, Poland.
概括
较高的体脂和较低的上肢功能与多发性硬化症 (MS) 患者的抑郁症状增加有关. 评估上肢功能对于管理多发性硬化及其相关的抑郁症状至关重要.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 康复医学 康复医学 康复医学
背景情况:
- 抑郁症显著影响多发性硬化症 (MS) 的生活质量和疾病进程.
- 了解导致MS抑郁的因素对于患者的护理和管理至关重要.
- 身体组成,运动功能和身体活动是对MS抑郁症状的潜在影响因素.
研究的目的:
- 研究多发性硬化症患者的身体组成,四肢运动功能,体力活动和抑郁症状之间的关系.
- 确定与MS群体中抑郁症风险更高相关的特定因素.
主要方法:
- 110名患有多发性硬化症 (MS) 的患者被评估是否有残疾 (EDSS),抑郁症状 (贝克抑郁 inventory-II),运动功能 (9洞 Peg 测试,定时25英尺步行) 和身体活动 (加速计).
- 使用后勤回归分析来确定变量与抑郁症状之间的关联.
- 统计分析包括多变量回归来确定抑郁症的显著预测因素.
主要成果:
- 在24.55%的参与者中存在抑郁症状.
- 与没有抑郁症的MS患者相比,患有抑郁症的MS患者在脂肪质量,定时25英尺步行 (T25-FW) 和9洞测试 (9-HPT) 主导的手表现上有显著差异.
- 增加脂肪和上肢运动功能的下降 (主导和非主导) 与更高的抑郁风险显著相关.
结论:
- 较高的体重和较低的上肢功能能力与MS患者抑郁症严重程度的增加有关.
- 对上肢功能的全面评估应纳入MS患者的常规运动功能的评估.
- 这些发现强调了在治疗多发性硬化症抑郁症时,关注身体组成和上肢功能的重要性.
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