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Updated: Jun 11, 2025

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
11:36

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones

Published on: July 25, 2019

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通过结构定义的K63-多基化链接素H1促进RNF168介导的核H2A泛基化

Qiang Shi1, Zhiheng Deng1, Liying Zhang1

  • 1New Cornerstone Science Laboratory, Tsinghua-Peking Joint Center for Life Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Center for Synthetic and Systems Biology, Department of Chemistry, Tsinghua University, Beijing, 100084, China.

Angewandte Chemie (International ed. in English)
|October 4, 2024
PubMed
概括

我们开发了一种新的化学合成方法 (CAEPL),以创建修改后的素H1.0蛋白质. 这种方法使我们能够研究素无处不在如何影响RNF168活性和蛋白质相互作用.

关键词:
化学蛋白质合成 化学蛋白质合成半氨酸结合的结合酶性蛋白质结合酶是一种酶性蛋白质结合.希斯在任何地方都存在.乌比基因连接酶是什么?

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