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肯尼亚妇女的凝血指标与月经流失之间的关联

Phidelis M Marabi^1,2, Stanslaus K Musyoki³, Fred Monari⁴

¹Department of Medical Laboratory Sciences, Faculty of Health Sciences, Kisii University, Kisii, Kenya.

African journal of laboratory medicine

|October 4, 2024

概括

肯尼亚西部的阴道流动与家族史上的出血障碍,高血栓激素时间 (PT) 和国际正常化比率 (INR) 的增加有关. 对凝血概况的评估对于诊断和管理至关重要.

科学领域:

血液学血液学血液学
妇女健康妇女健康
公共卫生公共卫生

背景情况:

阴道漏血对肯尼亚西部妇女的健康负担很大.
潜在的原因,特别是凝血障碍,在该地区仍未得到充分研究.

研究的目的:

调查肯尼亚西部有或没有阴流的妇女的凝血概况.
为了确定流血和特定的凝血参数之间的关联.
为了比较两个组之间的血小板形态.

主要方法:

一项涉及428名女性 (18-45岁) 的比较横截面研究,有和没有经月经.
评估社会人口统计学因素,前列血时间 (PT),激活的部分血栓塑时间,血时间,纤维素原,国际正常化比率 (INR) 和血小板计数.
分析凝血参数与阴潮之间的关联,确定增加的PT和INR水平.

主要成果:

患有月经流血的女性报告了更高频率的出血障碍家族病史 (p < 0.0001).
经历月经的女性表现出明显更高的PT (p < 0.0001) 和INR (p < 0.0001) 水平.
增加的PT (OR=2.129) 和INR (OR=7.479) 强烈与阴高相关 (p < 0.0001).

结论:

在这个肯尼亚西部人口中,月经不良与家族出血史,高血压和增加的INR有关.
常规的凝血概况查和对家族出血史的调查对于有效的阴道流诊断和管理至关重要.
在PT和INR的差异可以作为流经的预测指标.

关键词:

肯尼亚肯尼亚肯尼亚肯尼亚凝血是凝固的过程.阴道病是什么? 阴道病是阴道病.个人资料个人资料个人资料个人资料女人女人女人女人女人

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