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针对缺血性中风肠道微生物群的治疗方法:目前的进展和未来的方向

Zhiguo Mao^1,2, Jinying Zhang^1,2, Lin Guo^1,2

¹Department of Pharmacology, Henan University of Chinese Medicine, No. 156 Jinshui East Road, Zhengdong New District, Zhengzhou, Henan 450046, China.

Bioscience of microbiota, food and health

|October 4, 2024

概括

肠道微生物群通过复杂的机制影响缺血性中风 (IS) 的进展. 饮食和益生菌等干预措施通过调节肠-大脑轴来显示IS治疗的治疗潜力.

科学领域:

神经科学是一个神经科学.
微生物学微生物学
胃肠病学胃肠病学

背景情况:

缺血性中风 (IS) 是导致死亡和残疾的主要原因.
临床治疗IS受到狭窄的治疗时间窗口的限制.
肠道微生物群 (GM) 在整体健康和福祉中起着至关重要的作用.

研究的目的:

检查GM和IS之间的相互作用机制.
评估针对IS的转基因治疗干预措施.
探索转基因在中风治疗中的临床应用.

主要方法:

关于转基因和IS的最新科学文献的审查.
对神经,内分泌,免疫和代谢途径的分析.
评估干预措施,包括饮食,益生菌,FMT和抗生素.

主要成果:

微生物群-肠-大脑轴 (MGBA) 与IS进展密切相关.
转基因成分和功能显著影响IS.
各种干预措施显示了调节转基因治疗IS的潜力.

结论:

转基因对IS进行多方面的监管.
准GM为IS提供了新的治疗策略.
对基因转基因疗法的进一步研究可以改善中风患者的临床结果.

关键词:

内分泌通道的内分泌通道我们的肠道微生物群.免疫系统的免疫路径.缺血性中风中风微生物群-肠-大脑轴 (MGBA) 是一个神经通道的神经通道

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