加纳的罗塔病毒疫苗切换器是否符合程序预期? 国家监控数据的分析; 2018-2022年
Michael Rockson Adjei1,2, Justice Ofori Amoah3, George Bonsu4
1Department of Infectious Diseases, Center of Tropical Medicine and Travel Medicine, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Open forum infectious diseases
|October 4, 2024
概括
加纳在从Rotarix切换到Rotavac后,持续接种轮状病毒疫苗和减少腹. 接种疫苗的转换提供了程序性的好处,而不会对公共卫生结果产生负面影响.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 流行病学 流行病学
背景情况:
- 加纳在2020年从两剂Rotarix转向三剂Rotavac轮状病毒疫苗计划.
- 这种转换是由程序优势驱动的,包括成本效益和降低冷链要求.
研究的目的:
- 评估轮状病毒疫苗切换对疫苗接种趋势的影响.
- 评估疫苗接种后婴儿卫生机构门诊腹出院率的变化.
主要方法:
- 对2018-2022年免疫和腹监测数据的回顾性分析.
- 罗塔病毒疫苗产品的摄入量和腹相关的门诊出院率在接种疫苗之前和之后的比较.
主要成果:
- 罗塔病毒疫苗的接种率仍然很高,在两种疫苗类型 (Rotarix和Rotavac) 中都是可比的.
- 在接种疫苗覆盖率在转换前和转换后期间之间没有发现显著差异.
- 在接种疫苗之前 (12.4%) 和接种疫苗之后 (12.1%) 的腹门诊比例相似.
结论:
- 加纳的轮状病毒疫苗切换实现了计划目标,但没有对疫苗接种或腹发病率产生不良影响.
- 持续接种疫苗和减少腹表明过渡的成功.
- 学到的经验教训对于未来的疫苗计划修改来管理支出至关重要.
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