糖尿病人群中的脆弱性:印度北部的一项研究
Samyak Golchha1, Shankerdeep Sondhi1, Sunita Gupta1
1General Medicine, Maharishi Markandeshwar Institute of Medical Sciences & Research, Mullana, IND.
Cureus
|October 4, 2024
概括
50岁以上的糖尿病人与非糖尿病人 (29%) 相比,表现出明显更高的脆弱性流行率 (61.8%) 和严重程度. 虚弱的严重程度随着糖尿病的持续时间而增加,而不是血糖控制.
科学领域:
- 老年医学 老年医学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 虚弱,一个老年人增加脆弱性的综合征,与不良的健康结果有关.
- 糖尿病加剧了脆弱性,导致残疾和死亡率,但它们之间的联系需要进一步研究.
- 在糖尿病人群中早期识别脆弱性对于及时干预至关重要.
研究的目的:
- 调查糖尿病与50岁及以上个体的虚弱之间的关联.
- 为了比较糖尿病人和非糖尿病人之间虚弱的患病率和严重程度.
- 探索糖尿病持续时间,血糖控制和脆弱性之间的关系.
主要方法:
- 一项在印度进行的观察性,横截面研究.
- 采访了超过50岁的102名糖尿病患者和100名非糖尿病患者.
- 使用经过验证的埃德蒙顿脆弱度量表 (EFS) 来评估脆弱性.
主要成果:
- 在糖尿病患者 (61.8%) 与非糖尿病患者 (29%) 之间观察到明显更高的脆弱性.
- 在所有年龄组和性别的糖尿病患者中,虚弱的严重程度更为明显.
- 虚弱的严重程度与糖尿病持续时间有正相关性,但与HbA1c水平没有相关性.
结论:
- 糖尿病与50岁以上个体的脆弱性患病率和严重程度较高密切相关.
- 糖尿病的持续时间,而不是血糖控制,似乎影响了虚弱的严重程度.
- 研究结果强调了糖尿病患者的脆弱性查的必要性,特别是那些疾病持续时间较长的患者.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
Diabetes: Symptoms, Diagnosis, and Complications
515
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
515
Diabetes Mellitus: Overview and Type I Subtype
2.5K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.5K
Chronic Kidney Disease II: Clinical Manifestations
2
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
2
Carbohydrate Metabolism
10.8K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
10.8K
Pathophysiology of Diabetes
894
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
894


