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在先天性心脏手术患者中执行功能缺陷:患病率和呈现时间
Ty Elliot Hasselman1, Kara T Marriott2, Michele Verda3
1University of Illinois at Chicago School of Medicine, Chicago, IL, USA.
Cardiology in the young
|October 4, 2024
概括
即使在年轻时,接受心脏手术的儿童也面临影响执行功能的神经发育障碍的风险. 这些缺陷可能只会在儿童期晚些时候出现,因此需要持续监测.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 神经发育障碍 神经发育障碍
- 执行职能 执行职能 执行职能
背景情况:
- 在生命的第一年内进行先天性心脏手术会导致神经发育障碍的高风险,主要影响执行功能.
- 这项研究调查了经过一岁后手术的患者的神经发育风险,以及执行功能缺陷表现的年龄.
研究的目的:
- 为了确定生命的一年后的先天性心脏手术是否会降低神经发育障碍的风险.
- 确定儿科先天性心脏手术患者执行功能缺陷明显的年龄.
主要方法:
- 执行功能在四组儿科先天性心脏手术患者中进行了评估:高风险和低风险,有和没有遗传综合征.
- 使用了标准化评估,包括执行职能行为评级清单 (BRIEF) 和明尼苏达州执行职能量表.
- 执行职能缺陷的比率在风险组之间和与年龄相匹配的规范进行了比较,重点是缺陷出现的时间.
主要成果:
- 与规范数据相比,高风险和低风险组表现出更高的执行功能缺陷率.
- 低风险组显示出比高风险组更少的赤字趋势,尽管统计学意义尚未得到确立.
- 观察到执行功能缺陷在手术后的几年内表现出来,这表明发病时间延迟.
结论:
- 儿科先天性心脏手术患者,无论风险分层如何,都表现出显著的执行功能缺陷.
- 这些缺陷的延迟表现强调了长期神经发育监测和评估的必要性,因为儿童成熟了.
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