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Updated: Jun 11, 2025

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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面向新的抗炎药物:设计,合成和评估向XIAP-BIR2的分子

Marc Farag1, Nicolas Guedeney1, Florian Schwalen1

  • 1Department, Normandie Univ, UNICAEN, CERMN, bd Becquerel, F-14000, Caen, Cedex, France.

ChemMedChem
|October 4, 2024
PubMed
概括

研究人员开发了针对XIAP-BIR2的新型小分子,以抑制炎症. 化合物20c选择性地阻断NOD1/2通路,为克罗恩病等炎症性疾病提供潜在的治疗方法.

关键词:
抗炎药物是一种抗炎药物.基于碎片的药物设计.分子动力学分子动力学合成抑制剂 合成抑制剂在XIAP-BIR2中.

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