8. 8. 8. 这是一个很大的问题. 带状疹和疹后的神经疼痛
Elisabeth J M Adriaansen1, Julien G Jacobs2, Lisette M Vernooij1,3
1Pain Clinic, Department of Anesthesiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Pain practice : the official journal of World Institute of Pain
|October 4, 2024
概括
后神经痛 (PHN) 是继疹 (HZ) 之后的慢性疼痛. 干预性治疗,特别是背部根的脉冲射频 (DRG的PRF),为管理这种具有挑战性的疾病提供了新的选择.
科学领域:
- 神经学 神经学
- 疼痛管理 疼痛管理
- 传染性疾病 传染性疾病
背景情况:
- 后神经疼痛 (PHN) 是一种在疹病毒 (HZ) 感染后出现的衰弱性慢性疼痛状况.
- 急性HZ影响每1000人年3-5人,其中25%发展为PHN.
- PHN显著降低了生活质量,并且往往不耐治疗.
研究的目的:
- 更新对疹子 (HZ) 和后神经疼痛 (PHN) 的临床指南.
- 审查当前对HZ感染和PHN的干预治疗选择.
主要方法:
- 对HZ和PHN的诊断和治疗进行系统的文献综述.
主要成果:
- 早期的抗病毒治疗 (72小时内) 对急性HZ疼痛至关重要.
- 传统的PHN治疗包括局部药物 (素,利多卡因) 和口服药物 (抗抑郁药,抗药).
- 对于耐火性疼痛,可以考虑诸如外周注射和背部根的脉冲射频 (DRG的PRF) 等干预选择.
结论:
- 治疗急性HZ疼痛和PHN仍然具有挑战性.
- 干预性管理代表了PHN的新治疗途径.
- 背部根的脉冲射频 (DRG的PRF) 显示出作为一种有效的干预治疗的希望.
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