免疫疗法和新的治疗方法
Yaroslav Andrew Jakymec1, Justin Greiwe2, Jonathan A Bernstein2,3
1Department of Internal Medicine, Vassar Brothers Medical Center.
Current opinion in allergy and clinical immunology
|October 4, 2024
概括
过敏原免疫疗法创新显示出希望,新的方法改善了草过敏的症状. 然而,像内淋巴免疫疗法 (ILIT) 和皮内免疫疗法 (IDIT) 这样的新技术需要进一步的研究,因为结果和安全问题不一.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 免疫疗法研究 免疫疗法研究
背景情况:
- 过敏原免疫疗法 (AIT) 正在随着新的施用技术和法规而发展.
- 预计将对过敏性鼻炎和AIT进行更新的实践参数.
研究的目的:
- 审查当前的过敏原免疫治疗建议.
- 比较美国和欧洲的AIT实践.
- 检查新兴和实验性的AIT方法.
主要方法:
- 对过敏原免疫治疗的药物管理,时间表,疗效和安全性的文献综述.
- 美国和欧洲当前做法的比较.
- 对新型和实验性免疫疗法技术的分析.
主要成果:
- 使用新型过敏药的皮下免疫疗法 (SCIT) 对草过敏原显示出有效性.
- 内淋巴免疫疗法 (ILIT) 可能会增加不良事件.
- 皮内免疫疗法 (IDIT) 显示症状得分比安慰剂更差.
- 针对空气过敏原的皮肤上免疫疗法 (EPIT) 缺乏足够的数据.
结论:
- 在SCIT的创新是有效的草过敏.
- 新兴的AIT技术需要更多的研究.
- 新的法规旨在规范过敏原提取物处理.
相关概念视频
Tumor Immunotherapy
489
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
489
Cancer Vaccines
345
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
345
Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K
Cytotoxic T Cells-mediated Immune Response
857
Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
857


