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相关概念视频

Infertility in Males01:23

Infertility in Males

253
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
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相关实验视频

Updated: Jun 11, 2025

Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach
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使用炎症标志物预测静脉患者的不孕症风险的诺姆图.

Lihong Wang1,2, Lei Zheng1,2, Hui Jiang3

  • 1Department of Andrology and Sexual Medicine, The Second Hospital of Dalian Medical University, Dalian, China.

American journal of men's health
|October 4, 2024
PubMed
概括

这项研究开发了一种使用血液测试中的炎症标志物进行预测的诺姆图,以评估患有水 (VC) 的男性的不孕症风险. 诺米图有效预测不孕症,有助于静脉患者的临床决策.

关键词:
不孕不育 不孕不育 不孕不育这是一种炎症标志物.这个名字是名ogramogram.这种疾病的发病率是Varicocele.

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科学领域:

  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科
  • 生殖医学 生殖医学
  • 血液学 血液学 血液学

背景情况:

  • 静脉 (VC) 是男性不孕症的一个常见原因.
  • 在VC患者中预测不孕症风险仍然具有挑战性.
  • 炎症标志物可能在VC相关的不孕症中起作用.

研究的目的:

  • 开发和验证一个预测静脉患者不孕症风险的诺姆图.
  • 在VC中识别与不孕症相关的关键血液图炎症标志物.
  • 为早期风险评估和管理提供一个工具.

主要方法:

  • 对162名静脉患者 (2022-2024) 的回顾性分析.
  • 根据生育状况,分为不育和肥沃的群体.
  • 使用炎症标志物 (例如NLR,SIRI) 的物流回归和名录构造.
  • 使用ROC,校准和决策曲线分析进行验证.

主要成果:

  • 群体之间淋巴细胞,单细胞,红细胞,RDW,MCV,MPV,PDW,NLR,PLR,MPVPR和SIRI的显著差异 (p < .05).
  • 红细胞计数,PDW,NLR和SIRI被确定为不孕不育的独立预测因素.
  • 在验证队列中,该名录达到了0.869的AUC,证明了良好的预测性能.

结论:

  • 一种新型的诺米图有效地预测了使用易于获得的炎症标志物在静脉患者的不孕症风险.
  • 诺米图为VC男性不孕症的临床评估和管理提供了有价值的工具.
  • 建议进行进一步的外部验证,以确认名图的概括性.