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多普勒超声波在新生儿早发性败血症中的实用性:一个病例对照研究

A H Kasim^1,2, S A Mohammad¹, L A Habib¹

¹Radiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Journal of neonatal-perinatal medicine

|October 4, 2024

概括

新生儿早期发作的败血症 (EONS) 显著改变大脑血流 (CBF). 跨骨多普勒显示CBF增加和抗性降低,有助于早期诊断.

科学领域:

新生儿医学新生儿医学
儿科神经学儿科神经学
医疗成像医学成像

背景情况:

早期发作的败血症 (EONS) 是全球新生儿死亡的主要原因.
及时诊断EONS对于改善结果至关重要.
关于新生儿败血症早期脑血流 (CBF) 变化的数据有限.

研究的目的:

用EONS评估新生儿CBF速度和多普勒指数的变化.
评估这些CBF变化对EONS的诊断准确性.
在败血症期间调查新生儿大脑早期的血液动力学变化.

主要方法:

在出生后72小时内对99名新生儿进行了跨骨多普勒 (TCD) 检查.
大脑血液动力学,包括CBF速度和多普勒指数 (RI,PI,EDV,PSV),在前脑动脉 (ACA) 和中脑动脉 (MCA) 中进行测量.
该研究包括56名患有EONS的新生儿和43名没有败血症的年龄匹配对照.

主要成果:

患有EONS的新生儿表现出明显较低的电阻率指数 (RI) 和脉动率指数 (PI).
在患有EONS的新生儿的ACA和MCA中观察到更高的终端透缩速度 (EDV) 和峰值收缩速度 (PSV).
这些血液动力学变化在出生后72小时内就显现出来.

结论:

经皮多普勒评估显示,新生儿患有EONS时,大脑血动力学发生改变.
增加CBF和降低血管抵抗是EONS的关键指标.
TCD是一个有价值的,非侵入性的床边工具,用于快速诊断EONS.

关键词:

多普勒指数是指多普勒的指数.前脑动脉的前脑动脉早期发作的新生儿败血症中脑动脉中脑动脉通过骨的多普勒仪.

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