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相关概念视频

Aquaporins01:25

Aquaporins

4.8K
Aquaporins or AQPs are a family of integral membrane proteins whose primary function is to transport water, while some called aquaglyceroporins also transport glycerol. In addition, aquaporins have also been suspected to be involved in transporting volatile substances, such as carbon dioxide and ammonia, across membranes. Such AQPs that act as gas channels are often highly expressed in cells involved in the gaseous exchange, such as red blood cells, epithelial cells, and pulmonary capillaries.
4.8K
Reabsorption and Secretion in the DCT and Collecting Duct01:26

Reabsorption and Secretion in the DCT and Collecting Duct

938
The early phase of the DCT manages the reabsorption of approximately 10-15% of filtered water, 5–10% of filtered sodium, and 5–10% of filtered chloride. This process is facilitated by Na+–Cl− symporters in apical membranes and sodium-potassium pumps, as well as Cl− leakage channels in basolateral membranes. The early DCT also stands out as a site where parathyroid hormone (PTH) stimulates calcium reabsorption, depending on the body's requirements.
The distal...
938
Membrane Proteins01:30

Membrane Proteins

18.4K
Plasma membranes have integral transmembrane proteins involved in facilitated transport. These proteins are collectively referred to as transport proteins, and they function as either channels for the material or as carriers themselves. Channel proteins have hydrophilic domains exposed to the intracellular and extracellular fluids and a hydrophilic channel through their core that provides a hydrated opening for solutes to pass through the membrane layers. Passage through the channel allows...
18.4K
Pore Transport and Ion-Pair Transport01:17

Pore Transport and Ion-Pair Transport

389
Pore transport and ion-pair formation are critical mechanisms for the absorption and distribution of drugs in the body.
Pore transport, also known as convective transport, is a process where small molecules like urea, water, and sugars rapidly cross cell membranes as though there were channels or pores in the membrane. Although direct microscopic evidence is limited  but the concept of pores or channels is widely accepted based on physiological evidence. Despite the lack of direct...
389
Facilitated Transport01:19

Facilitated Transport

11.3K
The chemical and physical properties of plasma membranes cause them to be selectively permeable. Since plasma membranes have both hydrophobic and hydrophilic regions, substances need to be able to transverse both regions. The hydrophobic area of membranes repels substances such as charged ions. Therefore, such substances need special membrane proteins to cross a membrane successfully. In  facilitated transport, also known as facilitated diffusion, molecules and ions travel across a...
11.3K
ATP Driven Pumps I: An Overview01:27

ATP Driven Pumps I: An Overview

8.0K
ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
8.0K

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相关实验视频

Updated: Jun 11, 2025

Measuring the Osmotic Water Permeability Coefficient Pf of Spherical Cells: Isolated Plant Protoplasts as an Example
14:20

Measuring the Osmotic Water Permeability Coefficient Pf of Spherical Cells: Isolated Plant Protoplasts as an Example

Published on: October 8, 2014

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基于血红素的水体受体.

Savani Anbalagan1

  • 1Instytut Biologii Molekularnej i Biotechnologii, Wydział Biologii, Uniwersytet im. Adama Mickiewicza w Poznaniu.

Postepy biochemii
|October 4, 2024
PubMed
概括

细胞可以通过蛋白质水受体感知水,类似于气体受体. 这些水体受体可能广泛存在,在各种细胞位置发挥作用,并可能包括血红蛋白.

科学领域:

  • 细胞生物学 细胞生物学
  • 生物化学 生物化学
  • 生理学 生理学 生理学

背景情况:

  • 细胞感知水 (湿度感知) 对于生命至关重要,但机制仍然不清楚.
  • 现有的透传感器检测到溶液度,而不是直接检测到水.
  • 水感应进化为帮助生存和多细胞化.

研究的目的:

  • 为细胞水感应提出一种新的机制.
  • 为了确定涉及水检测的潜在蛋白质结构.

主要方法:

  • 根据结构相似之处,假设气体受体作为水体受体的作用.
  • 将拟议的功能扩展到各种细胞区域.

主要成果:

  • 建议基于血红素的气体受体中的气体结合部位可以结合水分子.
  • 提出这些蛋白质几乎在所有细胞中充当水体受体.
  • 假设水受体位于膜,细胞质和器官中.

结论:

  • 气体受体可能具有作为水体受体的双重功能.
  • 在细胞结构中预测水族受体的广泛分布.

更多相关视频

Culturing Primary Rat Inner Medullary Collecting Duct Cells
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Culturing Primary Rat Inner Medullary Collecting Duct Cells

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Human Serum Anti-aquaporin-4 Immunoglobulin G Detection by Cell-based Assay
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Human Serum Anti-aquaporin-4 Immunoglobulin G Detection by Cell-based Assay

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相关实验视频

Last Updated: Jun 11, 2025

Measuring the Osmotic Water Permeability Coefficient Pf of Spherical Cells: Isolated Plant Protoplasts as an Example
14:20

Measuring the Osmotic Water Permeability Coefficient Pf of Spherical Cells: Isolated Plant Protoplasts as an Example

Published on: October 8, 2014

16.0K
Culturing Primary Rat Inner Medullary Collecting Duct Cells
06:11

Culturing Primary Rat Inner Medullary Collecting Duct Cells

Published on: June 21, 2013

14.8K
Human Serum Anti-aquaporin-4 Immunoglobulin G Detection by Cell-based Assay
05:45

Human Serum Anti-aquaporin-4 Immunoglobulin G Detection by Cell-based Assay

Published on: April 5, 2019

23.2K
  • 血球蛋白被认为是一种潜在的水体受体候选物.