多年财政框架的SUMOylation协调裂变复合体,以促进压力诱导的线粒体分裂

Richard Seager1, Nitheyaa Shree Ramesh1, Stephen Cross2

  • 1School of Biochemistry, University of Bristol, Biomedical Sciences Building, Bristol BS8 1TD, UK.

Science advances
|October 4, 2024
PubMed
概括

在压力期间的线粒体碎片化受到MFF SUMOylation的调节,这是AMPK增强的过程. 这种SUMOylation控制了MiD结合,影响了DRP1复合体的形成和线粒体动态.

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