在儿科中,COVID-19静脉血栓塞栓症预防指南
Sara McElroy1, Emily Cramer2, Lauren Amos1
1Pediatric Hematology and Oncology, Children's Mercy Hospital, University of Missouri-Kansas City School of Medicine, 2401 Gillham Rd., Kansas City, MO 64108, United States of America.
Thrombosis research
|October 4, 2024
概括
COVID-19和MIS-C增加了血液凝块 (VTE) 的风险. 虽然许多符合条件的儿童接受了预防,但并非所有人都这样做. 标准风险因素准确地预测了这些患者的VTE预防的开始.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 传染病 传染病 传染病
- 血液学 血液学 血液学
背景情况:
- COVID-19和MIS-C是儿童VTE的重要危险因素.
- 在疫情期间制定了针对VTE预防的机构指南.
- 预防标准包括COVID-19与危险因素或MIS-C诊断.
研究的目的:
- 在COVID-19或MIS-C.的儿科患者中评估遵守VTE预防指南.
- 在这个队列中确定VTE和出血事件的发生率.
- 确定与VTE预防开始相关的因素.
主要方法:
- 回顾COVID-19或MIS-C.入院的患者的回顾性审查.
- 对VTE预防开始率的分析.
- 评估VTE和出血事件的发生情况.
- 后勤回归用于识别与预防相关的因素.
主要成果:
- 76%的符合条件的患者符合VTE预防的标准;65.6%开始预防.
- 与预防相关的因素包括血栓形成史,MIS-C诊断,ICU入院和中央静脉导管.
- 18名患者发生了静脉瘤;出血事件发生在12%的患者中.
- 与其他机构相比,VTE发病率相当于其他机构.
结论:
- 全球公认的VTE风险因素适用于确定COVID-19和MIS-C.儿童的血栓形成风险.
- 遵守VTE预防指南的情况有所不同,突出了需要改进的领域.
- 这项研究证实了小儿COVID-19和MIS-C群体的VTE风险.
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