托洛萨-亨特综合征的临床特征和结果;系统性审查
H Shafeeq Ahmed1, Deepak B Shivananda1, Sneha Reddy Pulkurthi2
1Bangalore Medical College and Research Institute, K.R Road, Bangalore, Karnataka 560002, India.
概括
托洛萨-亨特综合征 (THS) 是一种罕见的疾病,导致痛苦的眼动问题和头痛. 类固醇是主要的治疗方法,尽管恢复时间和一些复发,但提供了良好的结果.
科学领域:
- 神经学 神经学
- 眼科医生 眼科 眼科
- 系统审查是系统的审查.
背景情况:
- 托洛萨-亨特综合征 (THS) 是一种罕见的头痛疾病,其特征是痛苦的眼和神经.
- 1954年首次描述的THS涉及 carotid siphon周围的颗粒状炎症.
- 本系统性审查旨在巩固有关THS临床特征和结果的当前知识.
研究的目的:
- 系统地审查和总结有关托洛萨-亨特综合征的现有文献.
- 评估与THS相关的临床发现,治疗策略和结果.
主要方法:
- 在PubMed和Scopus数据库中进行了系统的文献搜索.
- 该审查遵循了PRISMA指南和一个注册的协议 (PROSPERO ID:CRD42023494249).
- 包括的研究检查了THS人口统计,临床表现,脑神经麻,诊断,治疗和结果.
主要成果:
- 包括11项主要针对亚洲人群的研究.
- 单侧轨道头痛,眼 (眼运动器,,三神经麻) 和洞穴鼻腔/轨道顶部的炎症是常见的.
- 类固醇 (IV和口服) 是主要的治疗方法,康复率和复发率从9-71%不一;其他免疫抑制剂的成功率不尽相同.
结论:
- 托洛萨-亨特综合征表现出各种症状,包括头痛和神经缺陷.
- 类固醇治疗,在各种形式,是有效的THS管理.
- 对于THS的整体预后通常是有利的,复发发病率很低.
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