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在西班牙广泛养的猪中对肝炎E病毒的纵向调查

Tomás Fajardo-Alonso¹, Ignacio García-Bocanegra², María A Risalde³

¹Departamento de Sanidad Animal, Grupo de Investigación GISAZ, UIC Zoonosis y Enfermedades Emergentes ENZOEM, Universidad de Córdoba, Córdoba, Spain.

Veterinary microbiology

|October 4, 2024

概括

肝炎E病毒 (HEV) 在广泛养的猪中普遍存在,在生产阶段具有很高的血清流行率. 这凸显了从家养猪向野生动物和人类传播动物感染的风险,需要监控.

科学领域:

兽医医学兽医医学兽医医学
动物传播疾病动物传播疾病
食品安全食品安全

背景情况:

肝炎E病毒 (HEV) 是一种新兴的动物性病原体,主要储存猪,野猪和红鹿.
户外养猪系统增加了HEV在家用野生动物界面传播的潜力.
欧洲食品安全局 (EFSA) 在整个猪粮食链中优先考虑HEV监测计划.

研究的目的:

在整个生产阶段评估在广泛养殖的猪中HEV循环的风险.
调查家养猪和野生动物 (野猪,红鹿) 之间接口的HEV传播动态.
为了确定这些宿主群体中循环的HEV基因型.

主要方法:

纵向抽样1452种广泛养殖的伊比利亚猪在繁殖,养殖和肥阶段.
对猪,野猪 (n=138) 和红鹿 (n=252) 的抗HEV抗体进行血清分析.
在来自猪和野生动物的血清样本中检测HEV RNA和基因定型.

主要成果:

猪中HEV抗体的高血清流行率 (85.7%),从30.4% (繁殖) 增加到97.0% (增肥).
与野猪 (31.9%) 和红鹿 (2.0%) 相比,肥猪的HEV血清流行率明显较高.
在猪 (基因型3f) 和野猪 (基因型3f和3m) 中检测到HEVRNA,表明跨物种传播.

结论:

广泛养的猪表现出高的HEV血清流行率,构成动物传播的重大风险.
在相似的家禽和野猪中存在动物性HEV基因型 (3f,3m),这凸显了综合监测的必要性.
控制措施和监测计划至关重要,特别是在广泛养猪的繁殖和养殖阶段.

关键词:

乙型肝炎E病毒的感染.帕斯拉赫佩病毒 (Paslahepevirus) 已经被发现.公共卫生公共卫生苏格兰的苏格兰人监测,野生动物,野生动物动物传染病是一种动物感染的疾病.

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