纵向研究的内在能力测量的发展:阿姆斯特丹纵向衰老研究
Yuwei Qi1, Laura A Schaap2, Benjamin D Schalet3
1Amsterdam UMC location Vrije Universiteit Amsterdam, Epidemiology and Data Science, the Netherlands.
Experimental gerontology
|October 4, 2024
概括
这项研究开发了内在能力 (IC) 评分,以衡量健康的衰老. 较高的IC分数与随着时间的推移更少的功能限制有关,有助于促进老年人的福祉.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 生物医学科学 生物医学科学
背景情况:
- 世界卫生组织 (WHO) 将内在能力 (IC) 介绍为健康衰老的关键因素.
- 内在能力涵盖了对老年人福祉至关重要的各种功能领域.
- 之前的研究缺乏全面的工具来测量IC及其纵向影响.
研究的目的:
- 开发和验证特定领域和复合IC分数.
- 评估不同年龄组的IC分数的构造有效性.
- 检查老年人IC分数和功能限制之间的纵向关系.
主要方法:
- 前性队列研究 (阿姆斯特丹长度老龄化研究) 随访10年.
- 利用因子分析和PLS-SEM的形成性,逐步方法,在五个领域 (活力,感官,认知,心理学,运动) 识别了18个IC指标.
- 评估结构有效性 (年龄组差异) 和标准有效性 (与功能限制相关).
主要成果:
- 开发了具有良好的构造有效性的特定领域和复合IC分数,显示与年龄相关的下降.
- 平均复合IC分数:70.9 (男性) 和69.7 (女性).
- 较高的复合IC得分与随着时间的推移更少的功能限制显著相关 (B=0.20,95%CI [0.19,0.22]).
结论:
- 开发的IC分数有效地区分了与年龄相关的内在能力下降.
- 复合IC分数作为纵向功能限制的可靠预测器.
- 这些验证的IC分数为未来的研究和战略提供了基础,以促进健康的衰老和福祉.
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