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Jianxia Hao1, Ning Zhu1, Lijun Song1

  • 1College of Chemical Engineering, Inner Mongolia University of Technology, Hohhot 010051, China; Inner Mongolia Engineering Research Center for CO(2) Capture and Utilization, Hohhot 010051, China; Key Laboratory of CO(2) Resource Utilization at Universities of Inner Mongolia Autonomous Region, Hohhot 010051, China.

概括

超临界抗溶剂技术创造了二/基甲基纤维素固体分散. 这提高了药物的溶解性和生物可用性,提供了具有良好的生物相容性的有希望的输送系统.

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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Factors Influencing Drug Absorption: Pharmaceutical Parameters01:28

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Factors Influencing Drug Absorption: Drug Dissolution01:27

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