预防性抗生素和皮质类固醇在息治疗中处方:回顾性研究
Claire Kruger1, Cian Lannon2, Ita Harnett3
1Palliative Medicine, Galway Hospice Foundation, Renmore, Galway, Ireland krugerc@tcd.ie.
在社区息治疗中接受口服皮质类固醇的患者面临更高的感染风险. 定期使用阿片类药物也会增加感染率,这表明高风险患者需要预防性抗生素.
科学领域:
- 抚慰性护理是一种缓解性护理.
- 传染病流行病学 传染病流行病学
背景情况:
- 社区息护理服务管理复杂的患者需求.
- 感染是缓和护理人群的一个重大问题.
- 类固醇使用在息治疗中很常见,但可能会增加感染风险.
研究的目的:
- 为了确定社区息护理患者服用类固醇是否有感染风险增加.
- 为了确定这个人群中感染的其他风险因素.
主要方法:
- 对被转诊到社区专家息护理服务的患者的回顾性图表审查.
- 统计分析以确定药物/疾病和感染之间的关联.
主要成果:
- 皮质类固醇使用与感染有显著的相关性 (39%对22%).
- 定期使用阿片类药物也与感染有显著的关联 (33%对15%).
- 男性性别,肺部疾病,糖尿病和免疫抑制剂显示与感染的关联不显著.
结论:
- 口服皮质类固醇显著增加社区息治疗中的感染率.
- 在接受皮质类固醇治疗的息治疗患者中考虑抗生素预防.
- 定期使用阿片类药物是感染的另一个重要风险因素.
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