在加拿大安大略省的老年人中,在护理院入院之前和之后的超多药学趋势在加拿大安大略省的老年人中
Laura C Maclagan1, Abby Emdin2, Anjie Huang1
1ICES (LCM, AE, AH, MAC, MT, CJM, SEB), Toronto, Ontario, Canada.
概括
超多药性,定义为使用10种以上药物,在老年人入院前后显著增加. 这一趋势凸显了在社区和长期护理环境中对药物审查的必要性.
科学领域:
- 老年学是一门学科.
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 超多药在老年人中越来越令人担忧,特别是那些过渡到养老院护理的人.
- 了解在护理院入院之前和之后的药物使用模式对于患者安全至关重要.
研究的目的:
- 调查加拿大安大略省老年人中超多药制的流行趋势,在养老院入院前后.
- 分析与超多药学相关的特定药物类别流行率的变化.
主要方法:
- 一项队列研究涉及61,470名75岁以上的成年人,他们在2017年至2020年期间入住了养老院.
- 使用卫生行政数据来评估高多药性 (≥10种分发的药物) 每季度在入院前10年和入院后1.5年.
主要成果:
- 在入院前的十年里,超多药性患病率从4.4%上升到12.0%,并在入院后进一步上升到13.8%.
- 在入院前观察到抗抑郁药物 (3倍),抗精神病药物 (7倍) 和胆酶抑制剂 (14倍) 的显著增加.
- 心血管疾病药物的使用在养老院入院前4-5年达到顶峰.
结论:
- 在护理院入院之前的十年里,超多药学几乎翻了三倍,不同药物类别的模式是不同的.
- 超多药在整个生命周期中的持续增长表明需要在社区和养老院环境中制定药物调和策略.
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