肌酸补充剂不会增加抗阻力训练效应在雌激素缺乏治疗前列腺癌患者:双盲随机试验
Ciaran M Fairman1, Kristina L Kendall2, Robert U Newton3
1Exercise Medicine Research Institute, Edith Cowan University, Australia; Arnold School of Public Health, University of South Carolina, USA.
Journal of science and medicine in sport
|October 4, 2024
概括
抵抗运动有效地改善质量,力量和身体功能,在接受雄激素剥夺疗法 (ADT) 的男性中. 在这项短期研究中,补充肌酸并没有提供额外的益处.
科学领域:
- 在瘤学瘤学.
- 运动生理学 运动生理学
- 营养科学 营养科学
背景情况:
- 抗雄激素剥夺疗法 (ADT) 与对瘦身量 (LM),肌肉力量和身体功能的有害影响有关.
- 众所周知,抵抗运动可以抵消这些ADT诱导的变化.
- 在这个人群中,肌酸补充对抗力运动的潜在附加益处尚不清楚.
研究的目的:
- 调查除了抵抗运动外,肌酸补充是否能进一步保护ADT诱导的下肢损失,力量和身体功能.
- 在接受ADT的前列腺癌患者中,比较抗力运动加肌酸与抗力运动加安慰剂的效果.
主要方法:
- 一个为期12周的随机对照试验,涉及30名前列腺癌患者接受ADT的男性.
- 参与者被分配到抵抗运动+安慰剂或抵抗运动+肌酸补充剂.
- 结果包括通过DXA测试的身体成分 (LM,脂肪量),肌肉强度和身体功能测试.
主要成果:
- 两组都在LM,肌肉力量和身体功能方面表现出显著的群体内改善 (p < 0.05).
- 对于任何结局措施,在补充肌酸的组和安慰剂组之间没有观察到统计学上显著的差异.
- 在这两种干预措施中都没有报告任何不良事件.
结论:
- 一个短期的阻力运动计划有效地改善了LM,肌肉力量和身体功能在接受ADT的男性.
- 在这种情况下,肌酸补充似乎没有提供除了抵抗运动之外的额外益处.
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