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Updated: Jun 13, 2025

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NPC1将胆固醇贩运与微质形态通过胃细胞组联系起来

Joanna Zareba1, Elena F Cattaneo1, Ambra Villani1

  • 1Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.

Nature communications
|October 4, 2024
PubMed
概括

尼曼 - 皮克疾病C型 (NPC) 导致微质细胞由于胆固醇在胃细胞体中积累而改变形状. 这种缺陷会损害脑细胞增生,增加脑细胞的脆弱性.

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