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Updated: Jun 11, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

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通过基因组剖析来评估BRCA突变患者的先发性乳腺组织的癌症风险评估

Takeshi Hirose1,2, Masachika Ikegami1, Kumiko Kida3

  • 1Division of Cellular Signaling, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

NPJ breast cancer
|October 4, 2024
PubMed
概括

在正常乳腺组织中的克隆扩张,通过新的克隆性得分来表明,可以在病理检测之前预测BRCA1/2载体的乳腺癌风险. 这一发现为早期预防策略提供了潜力.

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