在患有芬坦生理学的儿科患者中确定虚弱及其危险因素
Megan M Wilde1, Kurt R Schumacher2, Sunkyung Yu2
1Division of Pediatric Cardiology, Department of Pediatrics, Indiana University, Indianapolis, IN, USA.
Pediatric cardiology
|October 4, 2024
概括
三分之一的患有Fontan循环的儿科患者是脆弱的,体验了减少的身体功能和增加的住院治疗. 这些年轻患者的脆弱性往往没有被医疗保健提供者认可,需要改进查.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 老年学是一门学科.
- 临床医学 临床医学
背景情况:
- 虚弱是一种已知的成人综合征,与不良健康结果有关.
- 它在儿科患者群体的患病率和影响,特别是那些患有单心室心脏病的人群,仍未得到充分研究.
- 丰丹循环带来了独特的生理挑战,可能会影响儿童的脆弱发展.
研究的目的:
- 为了确定患有Fontan循环的儿科患者的脆弱性患病率.
- 为了确定与这个队列中的脆弱性相关的风险因素.
- 将客观的脆弱性评估与提供者估计进行比较,并评估对生活质量的影响.
主要方法:
- 一个单一中心的前性队列研究,涉及54名儿科患者 (10-21岁) 在Fontan息后进行.
- 使用修改后的Fried脆弱性评估来测量缓慢,软弱,疲劳,收缩和身体活动.
- 评估了患者报告的生活质量 (QOL),并将脆弱性得分与提供者估计进行了比较.
主要成果:
- 33%的患者被确定为虚弱,48%为虚弱前.
- 常见的虚弱领域包括缓慢 (93%),虚弱 (41%) 和身体活动减少 (39%).
- 脆弱患者的身体功能得分 (PedsQL) 显著降低,并与失去蛋白质的肠道病变和最近住院住院有关.
结论:
- 在患有Fontan循环的儿科患者中,脆弱性很普遍,影响身体功能和医疗保健利用率.
- 提供者对脆弱性的认识很差,突出了临床评估中的差距.
- 在这个脆弱的儿科群体中,急需加强查和针对脆弱性的有针对性的支持.
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