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回声时间对肺通风和输液的影响,通过使用多回声超短回声时间采集的相位解析功能性肺 (PREFUL) MRI 来得出

Lea Behrendt^1,2, Marcel Gutberlet^1,2, Andreas Voskrebenzev^1,2

¹Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

NMR in biomedicine

|October 5, 2024

概括

非对比增强的HMRI显示了肺呼吸/输液 (V/Q) 评估的前景. 然而,更长的回声时间 (TE) 显著改变了V/Q参数,表明更短的TE对于精确的肺成像至关重要.

科学领域:

放射学放射学是一门学科.
肺部医学肺部医学
医疗成像医学成像

背景情况:

非对比增强的HMRI是一种有前途的肺呼吸/输液 (V/Q) 评估技术.
回声时间 (TE) 对从相位解析功能性肺部 (PREFUL) MRI 获得的 V/Q 参数的影响尚不清楚.

研究的目的:

为了研究不同回声时间 (TE) 对使用PREFULMRI获得的肺V/Q参数的影响.
为了评估V/Q测量的可重复性在不同的TEs.

主要方法:

开发了一个2D多回声超短TE (UTE) MRI序列与辐射采集.
从48名参与者 (25名健康人,6名喘患者,17名肺纤维化患者) 获取的数据,使用6种不同的TEs (0.074.12 ms).
计算区域通风 (RVent),流量循环交叉相关度量 (FVL-CM),规范 perfusion-weighted 信号 (QN) 和 V/Q 缺陷百分比 (VDP/QDP).

主要成果:

与最短的TE (TE₁) 相比,在TEs 3-6中观察到V/Q参数的显著差异.
对TEs 1-2的重复性很好,在较长的TEs中变化系数 (CoV) 增加.
在较长的TEs中,RVent表现出T2*依赖性,这可能会影响通风评估.

结论:

回声时间显著影响由PREFULMRI获得的肺V/Q参数.
建议较短的回声时间 (TE_1-2) 进行准确和可重复的V/Q评估.
在较长的TEs中,RVent的T2*依赖性需要仔细选择回声时间,以获得可靠的肺成像.

关键词:

很可能是Preful.美国工业大学 (UTE)肺肺肺肺肺肺肺肺肺多重回声多重回声 perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion 这是一个非常重要的方法,它可以让一个人的身体变得更加舒适,可以让一个人的身体变得更加舒适,可以让一个人的身体变得更加舒适通风系统的通风系统.

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