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Updated: Jun 11, 2025

Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry
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Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry

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矩阵辅助激光脱/电离质谱成像作为手术分子组织病理学的新工具

Cinzia Cagnoli1, Dalia De Santis1, Claudio Caccia2

  • 1Epilepsy Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Epilepsia
|October 5, 2024
PubMed
概括

矩阵辅助激光消化/电离质谱成像 (MALDI-MSI) 可以识别组织的独特特征. 这种空间奥米克技术有助于分类焦皮质发育不良 (FCD),并可能改善手术结果的患者分层.

关键词:
在FFPE的FFPE.的手术 的手术焦点皮层发育不良症人类组织的人类组织.质谱仪成像成像 质谱仪成像成像酸是一种酸.

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Matrix-Assisted Laser Desorption Ionization (MALDI)01:08

Matrix-Assisted Laser Desorption Ionization (MALDI)

Matrix-assisted laser desorption ionization (MALDI) is a powerful analytical technique used in mass spectrometry. It enables the identification and characterization of various biomolecules, including proteins, peptides, nucleic acids, and carbohydrates. MALDI spectrometry is widely employed in biological and medical research, as well as in fields like pharmacology and biochemistry.
The analyte of interest, a biomolecule or a mixture of biomolecules, is mixed with a suitable matrix material. The...
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