早期与晚期食的比较分析 皮肤穿后内镜胃口管放置:系统性审查和元分析
Mahesh Gajendran1, Eric Smith2, Priyadarshini Loganathan3
1Gastroenterology, University of Texas Health Science Center, San Antonio, TX, USA. gajendran@uthscsa.edu.
Digestive diseases and sciences
|October 5, 2024
概括
通过皮肤内镜胃口 (PEG) 管放置后4小时内开始输管养是安全有效的. 在PEG放置后早期养不会增加并发症或死亡率,提供潜在的好处,如减少住院时间.
科学领域:
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
- 医疗程序 医疗程序
背景情况:
- 通过皮肤内镜胃口切除术 (PEG) 放置后延迟开始输管养是常见的,尽管有证据支持早期养.
- 之前的元分析表明,在PEG放置后4小时内开始输管养是安全的.
研究的目的:
- 进行更新的元分析,比较PEG放置后的早期 (≤4小时) 与延迟 (>4小时) 输管养.
- 评估早期养对手术后72小时内并发症和死亡率的影响.
主要方法:
- 在PubMed,EMBASE和Web of Science系统搜索随机对照试验 (RCT) 到2022年6月.
- 对六项涉及PEG管安置的成年患者的RCT的分析.
- 聚合几率比率 (95% CI) 用于计算并发症和死亡率.
主要成果:
- 分析包括了早期养组的212名患者和延迟养组的215名患者.
- 早期养时没有观察到总并发症事件的显著增加 (OR 0.86,CI 0.51-1.45,p=0.58).
- 发烧,吐和局部感染等特定并发症在两组之间也没有显著差异.
结论:
- 在PEG放置后早期养 (≤4小时) 是安全的,耐受性良好,并没有增加并发症或死亡风险.
- 早期开始输液养是延迟养的有效替代方案,可能导致更短的住院时间和更低的医疗保健费用.
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