高成本,一次性潜在治疗疗法的管理入口协议:一个框架和计算工具来确定它们的适用性
Marcelien H E Callenbach1, Rick A Vreman1,2, Christine Leopold1
1Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands.
PharmacoEconomics
|October 5, 2024
概括
本研究引入了一个框架和工具,用于比较高成本疗法的支付模式,帮助决策改善患者获得创新治疗的机会. 它有助于评估财务影响和优化报销策略.
科学领域:
- 卫生经济学 卫生经济学
- 制药政策 制药政策
- 医疗保健管理的管理
背景情况:
- 高成本,一次性治疗疗法带来了独特的报销挑战.
- 患者及时获得创新的健康干预措施至关重要.
- 现有的支付模式可能无法充分解决新型治疗的经济复杂性.
研究的目的:
- 开发一个框架和计算工具来比较高成本,一次性治疗疗法的支付模式.
- 支持决策过程,实施合适的支付模式.
- 提高患者及时获得创新的健康干预措施的机会.
主要方法:
- 制定了一个框架,以指导选择合适的支付模式.
- 创建了一个基于Excel的计算工具来量化成本,预算影响和收益 (质量调整后的寿命年).
- 用于展示,使用了onasemnogene abeparvovec,brexucabtagene autoleucel和etranacogene dezaparvovec的案例研究.
主要成果:
- 该框架指导着将支付模式与疾病和治疗特征相匹配.
- 该计算工具评估了价格折扣和基于结果的差价支付模型的财务影响.
- 不同的支付模式产生不同的财务后果,基于长期有效性假设.
结论:
- 该框架为决策者提供了关于支付模式财务后果的见解.
- 它通过澄清基于治疗特征的最佳选择来帮助退款谈判.
- 这种工具可以为创新疗法提供更好的财务规划.
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