患有状细胞病的成年人呼吸系统表型和医疗保健利用模式
Atu Agawu1, Nii Nortey2, Charleen Jacobs2
1Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA.
Blood advances
|October 5, 2024
概括
患有状细胞疾病和呼吸道症状的成年人,即使没有喘,也显著增加了医疗保健使用率. 需要进一步的研究来了解原因,并为这个脆弱的人群寻找干预措施.
科学领域:
- 肺部医学 肺部医学
- 血液学 血液学 血液学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 患有状细胞疾病 (SCD) 和喘的成年人面临更高的死亡率和医疗保健利用率.
- 在没有喘的SCD患者中,咳和喘息等呼吸系统症状也可能表明医疗保健需求增加.
- 了解这些呼吸系统表型对于管理SCD并发症至关重要.
研究的目的:
- 描述呼吸系表型与SCD成年人医疗利用之间的关联.
- 为了比较患有喘,呼吸道症状或两者都没有的SCD患者的医疗保健利用模式.
主要方法:
- 使用国家医疗保健数据库 (2012-2014) 对29952名患有SCD的成年人进行横截面研究.
- 呼吸系统表型定义为SCD+喘,SCD+呼吸系统症状,或SCD+没有.
- 多变量后勤和负二项式回归模型,根据人口统计和健康的社会决定因素进行调整.
主要成果:
- 3.4%的SCD成年人有间歇性呼吸道症状;15.6%患有喘.
- 与没有呼吸道症状的人相比,患有呼吸道症状的人每年住院住院次 (43%) 和急诊室访问次数 (60%) 较高.
- 喘患者住院次较高 (48%对37%),但ED访问次数较少 (62%对86%),而不是呼吸系统症状患者.
结论:
- 经历间歇性呼吸道症状的SCD成年人显著增加了医疗保健利用率.
- 这一发现凸显了对SCD呼吸系统问题的潜在原因和潜在干预措施的进一步调查的需要.
- 在SCD中识别和管理呼吸系统表型对于改善患者的治疗结果和减少医疗保健负担至关重要.
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