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Updated: Jun 11, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

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YAP/TAZ驱动了诺奇和血管生成机制的调节

Margot Passier1,2, Katie Bentley3,4, Sandra Loerakker1,2

  • 1Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.

NPJ systems biology and applications
|October 5, 2024
PubMed
概括

这项研究模拟了细胞外矩阵硬度如何影响血管形成. 计算模拟揭示了YAP/TAZ-Notch路径交叉通话,通过操纵细胞力学来控制血管生成的策略.

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