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Updated: Jun 11, 2025

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通过以4,4'-双氨酸为媒介的芳香酸还原来激活前药物

Qing Wang1, Yikang Song1, Shuowei Yuan1

  • 1School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China.

Nature communications
|October 5, 2024
PubMed
概括

这项研究引入了一种新的生物对等反应,使用4,4'-双二来进行芳香化还原. 这种有机催化方法使细胞和生物体中可控的前药激活成为可能,进步了癌症治疗和化学生物学.

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