成年人中喘和内脏脂肪组织之间的关联,NHANES 2011-2018年的横截面研究
Tong Lin1, Haiyan Mao1, Shanshan Huang1
1Department of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, China.
Scientific reports
|October 5, 2024
概括
内脏脂肪组织 (VAT) 的增加与喘风险的增加有关,特别是在女性和老年人中. 管理增值税可能有助于降低喘风险并改善呼吸系统健康.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 内分泌学 在内分泌学.
- 肥胖问题研究研究
背景情况:
- 喘是一种慢性炎症性呼吸道疾病,影响全球数百万人.
- 肥胖,特别是内脏脂肪组织 (VAT),分泌与代谢和心血管疾病相关的因素.
- 现有的关于VAT和喘之间具体联系的研究是有限的.
研究的目的:
- 调查内脏脂肪组织 (VAT) 与喘风险之间的关联.
- 探索这种关系中的潜在效果修饰因素和非线性关联.
主要方法:
- 使用了NHANES数据库 (2011-2018) 共有11,137名参与者.
- 进行了多变量回归分析,按增值税水平分层,并调整了混因素.
- 进行了子组相互作用和非线性分析.
主要成果:
- 与非喘患者 (455g) 相比,喘患者的增值税 (529g) 显著更高.
- 每增加200克的增值税与喘风险上升10.4%-20.8%相关.
- 在女性和40岁以上的人群中观察到更强的关联;确定了一个J形关系.
结论:
- 增加的增值税与喘风险增加有关,特别是在女性和老年人中.
- 在喘风险评估中应考虑增值税.
- 针对过度内脏脂肪的有针对性的干预措施可以降低喘风险.
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