在生物假肢与机械门中,大动脉膜更换后的长期结果
Abeline R Watkins1, Ryaan El-Andari2, Nicholas M Fialka2
1Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Heart & lung : the journal of critical care
|October 6, 2024
概括
对于50-70岁的接受主动脉置换 (AVR) 的患者,生物假体和机械的长期存活率相似. 生物假体是一个合理的选择,尽管机械提供更长的耐用性.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 生物医学工程 生物医学工程
背景情况:
- 大动脉膜疾病 (AVD) 是导致心脏膜疾病 (VHD) 死亡的一个重要原因.
- 目前的指导方针建议50岁以下的患者使用机械门,70岁以上的患者使用生物假体门进行主动脉置换 (AVR).
研究的目的:
- 在接受AVR的50-70岁患者中,比较生物假体与机械门的长期结果.
- 为了评估这个特定年龄组的门类型之间的死亡率,发病率和重新操作率的差异.
主要方法:
- 对接受AVR的744名患者 (2:1比) 的倾向匹配分析.
- 结果的比较,包括生物假体和机械接收者之间的死亡率,发病率和重新操作率.
主要成果:
- 两组之间没有观察到30天死亡率或并发症率的显著差异.
- 在1,5年和15年的长期死亡率对于生物假体和机械门都是相似的.
- 虽然5年和10年后的重复手术率相似,但生物假体门在15年后的重复手术可能性更高 (21.2%对比9.7%).
结论:
- 在50-70岁的患者中,大动脉置换产生了类似的长期结果,无论门类型如何.
- 生物假体门是一个可行的选择,因为其低的重新操作率,死亡率和避免抗凝血.
- 机械门对年轻患者保持了耐用性的优势,而生物假体门适合50-70岁的年龄组.
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