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Updated: Jun 11, 2025

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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瘤微环境激活的聚类纳米颗粒用于瘤性免疫治疗.

Zhihui Guo1, Tianze Huang1, Xueli Lv2

  • 1Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, PR China; School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, 230026, PR China.

Biomaterials
|October 6, 2024
PubMed
概括

这项研究开发了pH敏感的纳米颗粒 (DNP) 来屏蔽阴离子解聚 (PLP). 在酸性瘤环境中,DNP释放PLP,改善癌细胞选择性并减少毒性,以有效的免疫疗法.

关键词:
癌症免疫疗法癌症免疫疗法阴阳性多化物.免疫原性细胞死亡瘤治疗疗法 瘤治疗疗法对于pH值的敏感性

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